Internal Medicine Practice

dr. med. univ. albrecht wenzel

Leipzig · Georg-Schumann-Straße 257

When sleep disrupts your metabolism.

Sleep medicine (in training) Obesity specialist (DAG-DDG) Nutritional medicine (LÄK) Consultations in English

The Night — Sleep Disorders & Apnea

What happens at night is decided by day.

In obstructive sleep apnea, the throat muscles relax during sleep and the airways narrow — often dozens of times per hour. Most people notice nothing but daytime fatigue. We clarify what happens at night: on an outpatient basis, in your own bed.

Up to 90 %

of people with severe obesity have obstructive sleep apnea — most without knowing it.Estimate; cf. S3 guideline on sleep-related breathing disorders (DGSM, AWMF 063-001).

6 not 8

Sleeping 6 instead of 8 hours measurably raises ghrelin and lowers leptin — two hormones that directly control when hunger arises.Spiegel et al., Ann Intern Med 2004.

The Dawn — The Vicious Cycle

Sleep and weight — one cycle.

Sleep apnea fragments sleep and shifts the hunger hormones: more ghrelin, less leptin, more cortisol. The result is more appetite and an unfavourable fat distribution — including in the throat, which in turn worsens the apnea. This is exactly where treatment begins: at both ends.

10 %

less body weight can reduce the number of nightly breathing pauses by 30 to 50 % — in suitable cases, CPAP therapy can be reduced or stopped.Peppard et al., JAMA 2000; Tuomilehto et al., Am J Respir Crit Care Med 2009.

S3 Guideline

The guideline on sleep-related breathing disorders explicitly recommends weight reduction for overweight patients.

Daytime fatigue despite eight hours of sleep. Weight that won't drop despite cutting back.
Sometimes these problems are connected — and sometimes the solution has to do with sleep.

The Day — Obesity Treatment

Weight is the strongest lever.

Weight reduction acts on the cause of sleep apnea — and improves blood pressure and metabolism at the same time. The foundation is always lifestyle: nutrition, movement and sleep. Medication can support that path — it cannot replace it. We treat according to the S3 obesity guideline: multimodal, destigmatising, and guided by what measurement and findings actually show.

The Day — Medical Options

GLP-1 — when the injection supports.

GLP-1 receptor agonists and dual incretins (semaglutide, tirzepatide) amplify the effect of the body's own satiety hormones. Recent studies show that in obese sleep apnea patients, tirzepatide can markedly reduce breathing pauses — alongside weight loss. The decision is always made by the person, not the medication.

The Practice

About the doctor.

dr. med. univ. Albrecht Wenzel — internist in Leipzig

dr. med. univ. Albrecht Wenzel

Board-certified specialist in general internal medicine, focusing on the metabolic syndrome and its interconnections — in particular the interplay of sleep and weight.

Treatment is consistently based on the current S3 guidelines of the professional societies.

  • Obesity specialistDAG-DDG 2024
  • Nutritional medicineLÄK 2024
  • DiabetologyLÄK 2024
  • Sleep medicinein training

More about the doctor

This site shows the Sleep & Weight focus. The practice also offers diabetology and full primary care — to the main practice →

Contact

Contact & opening hours.

0341 5210871
info@internist-wenzel.de

Georg-Schumann-Straße 257 · 04159 Leipzig · Germany
Online appointments: Open Doctolib

Opening hours
Monday08:00 – 12:00 · 12:30 – 15:00
Tuesday08:00 – 12:00 · 13:00 – 18:00
Wednesday08:00 – 12:00 · 12:30 – 15:00
Thursday08:00 – 12:00 · 13:00 – 16:00 (private)
Friday08:00 – 12:00
Acute walk-in (no appointment)
Mon & Tue08:00 – 09:30
Wed – Fri08:00 – 09:00

Emergency: In medical emergencies, please call emergency services on 112.

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